Projects
Pending
Selected Publications
Barger N, Keiter J, Kreutz A, Krishnamurthy A, Weidenthaler C, Martínez-Cerdeño V, Tarantal AF, and Noctor SC. Microglia: An intrinsic component of the proliferative zones in the fetal rhesus monkey (Macaca mulatta) cerebral cortex. Cereb Cortex 29:2782-2796, 2019. PMCID: PMC6611465
Batchelder CA, Keyser JL, Lee CC, and Tarantal AF. Characterization of growth, glomerular number, and tubular proteins in the developing rhesus monkey kidney. Anat Rec (Hoboken) 296:1747-1757, 2013. PMCID: PMC4272578
Batchelder CA, Lee CCI, Duru N, Baker C, Swainson L, McCune JM, and Tarantal AF. Myeloid-lymphoid ontogeny in the rhesus monkey (Macaca mulatta). Anat Rec (Hoboken) 297:1392-1406, 2014. PMCID: PMC4120262
Batchelder CA, Lee CCI, Martinez ML, and Tarantal AF. Ontogeny of the kidney and renal developmental markers in the rhesus monkey (Macaca mulatta). Anat Rec (Hoboken) 293:1971-1983, 2010. PMCID: PMC316314
Berg E, Gill H, Marik J, Ogasawara A, Williams S, van Dongen G, Vugts D, Cherry SR, and Tarantal AF. Total-Body PET and highly stable chelators together enable meaningful 89Zr-antibody PET studies up to 30 days after injection. J Nucl Med 61:453-460, 2020. PMCID: PMC7067524
Eid FE, Chen AT, Chan KY, Huang Q, Zheng Q, Tobey IG, Pacouret S, Brauer PP, Keyes C, Powell M, Johnston J, Zhao B, Lage K, Tarantal AF, Chan YA, and Deverman BE. Systematic multi-trait AAV capsid engineering for efficient gene delivery. Nature Communications 15:6602, 2024. PMCID: PMC11297966
Jimenez DF, Leapley AC, Lee CI, Ultsch MN, and Tarantal AF. Fetal CD34+ cells in the maternal circulation and long-term microchimerism in rhesus macaques (Macaca mulatta). Transplantation 79:142-146, 2005.
Kim H, Zenhausern R, Gentry K, Lian L, Huayamares S, Radmand A, Loughrey D, Podilapu A, Hatit MZC, Ni H, Li A, Shajii A, Peck HE, Han K, Hua X, Jia S, Martinez M, Lee C, Santangelo PJ, Tarantal AF, and Dahlman JE. Lipid nanoparticle-mediated mRNA delivery to CD34+ cells in rhesus monkeys. (In Press)
Krueger MR, Fishman-Williams E, Simó S, Tarantal AF, and La Torre A. Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the developing rhesus monkey retina. Differentiation 135:100743, 2024. PMCID: PMC10868720
Kulhankova K, Traore S, Cheng X, Benk-Fortin H, Hallée S, Harvey M, Roberge J, Couture F, Kohli S, Gross TJ, Meyerholz DK, Rettig GR, Thommandru B, Kurgan G, Wohlford-Lenane C, Hartigan-O'Connor DJ, Yates BP, Newby GA, Liu DR, Tarantal AF, Guay D, and McCray PB Jr. Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo. Nature Communications 14:8051, 2023. PMCID: PMC10698009
Lee CI, Fletcher M, and Tarantal AF. Effect of age on the frequency, cell cycle, and lineage maturation of rhesus monkey (Macaca mulatta) CD34+ and hematopoietic progenitor cells. Pediatr Res 58:315-322, 2005.
Lee CI, Jimenez DF, Kohn DB, and Tarantal AF. Fetal gene transfer using lentiviral vectors and the potential for germ cell transduction in rhesus monkeys. Hum Gene Ther 16:417-425, 2005.
Liang SQ, Navia A, Ramseier M, Zhou X, Martinez ML, Lee CC, Zhou C, Wu J, Xie J, Su Q, Wang D, Flotte TR, Anderson DG, Tarantal AF, Shalek A, Gao G, Xue W. AAV5 delivery of CRISPR/Cas9 mediates genome editing in the lungs of young rhesus monkeys. Human Gene Therapy 2024 May 20. doi: 10.1089/hum.2024.035.
Pekrun K, Stephens CJ, Gonzalez-Sandoval A, Goswami A, Zhang F, Tarantal AF, Blouse G, and Kay MA. Correlation of antigen expression with epigenetic modifications after rAAV delivery of a human factor IX variant in mice and rhesus macaques. Molecular Therapy 32:2064-2079, 2024. PMCID: PMC11286812
Rossano S, Toyonaga T, Berg E, Lorence I, Fowles K, Nabulsi N, Ropchan J, Li S, Ye Y, Felchner Z, Kukis D, Huang Y, Benveniste H, Tarantal AF, Groman S, Carson RE. Imaging the fetal nonhuman primate brain with SV2A positron emission tomography (PET). Eur J Nucl Med Mol Imaging 49:3679-3691, 2022. PMCID: PMC9826644
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB Jr, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, and Zhou J; SCGE Consortium. The NIH Somatic Cell Genome Editing program. Nature 592:195-204, 2021. PMCID: PMC8026397
Smith TJ, Elmore ZC, Fusco RM, Hull JA, Rosales A, Martinez M, Tarantal AF, and Asokan A. Engineered IgM and IgG cleaving enzymes for mitigating antibody neutralization and complement activation in AAV gene transfer. Molecular Therapy 32:2080-2093, 2024. PMCID: PMC11286816
Tarantal AF and Lee CCI. Long-term luciferase expression monitored by bioluminescence imaging after adeno-associated virus-mediated fetal gene delivery in rhesus monkeys (Macaca mulatta). Hum Gene Ther 21:143-148, 2010. PMCID: PMC2829449
Tarantal AF, Lee CCI, Kukis D, and Cherry SR. Radiolabeling to monitor cell trafficking and engraftment of human peripheral blood stem cells by PET in young rhesus monkeys. PLoS One 8:e77148, 2013. PMCID: PMC3789702
Tarantal AF, Lee CCI, Martinez ML, Asokan A, and Samulski RJ. Systemic and persistent muscle gene expression in rhesus monkeys with a liver de-targeted adeno-associated virus (AAV) vector. Hum Gene Ther 28:385-391, 2017. PMCID: PMC5444483
Tarantal AF, Noctor SC, and Hartigan-O'Connor DJ. Nonhuman Primates in Translational Research. Annu Rev Anim Biosci 10:441-468, 2022. PMCID: PMC9339229
Tarantal AF and Skarlatos SI. Center for Fetal Monkey Gene Transfer for Heart, Lung, and Blood Diseases: an NHLBI resource for the gene therapy community. Hum Gene Ther 23:1130-1135, 2012. PMCID: PMC3498881